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Levitra Prescription Drugs

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Levitra

Uses

Vardenafil is used to treat male sexual function problems (impotence or erectile dysfunction -ED). In combination with sexual stimulation, vardenafil works by increasing blood flow to the penis to help a man get and keep an erection.

How to use Levitra

Read the Patient Information Leaflet provided by your pharmacist before you start taking vardenafil and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor, usually as needed. Take vardenafil, with or without food, about 1 hour before sexual activity. Do not take more than once daily. Doses should be taken at least 24 hours apart.

The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.

Tell your doctor if your condition does not improve.

Side Effects

Headache. flushing, stuffy/runny nose. or dizziness may occur. Vision changes such as increased sensitivity to light, blurred vision. or trouble telling blue and green colors apart may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Sexual activity may put extra strain on your heart. especially if you have heart problems. If you have heart problems and experience any of these serious side effects while having sex. stop and get medical help right away: severe dizziness, fainting. chest/jaw/left arm pain, nausea .

Rarely, sudden decreased vision. including permanent blindness, in one or both eyes (NAION) may occur. If this serious problem occurs, stop taking vardenafil and get medical help right away. You have a slightly greater chance of developing NAION if you have heart disease. diabetes. high cholesterol. certain other eye problems (“crowded disk”), high blood pressure. if you are over 50, or if you smoke.

Rarely, a sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness, may occur. Stop taking vardenafil and get medical help right away if these effects occur.

In the rare event you have a painful or prolonged erection lasting 4 or more hours, stop using this drug and get medical help right away, or permanent problems could occur.

Get medical help right away if you have any very serious side effects, including: fast/irregular heartbeat. seizures. temporary memory loss .

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction. including: rash. itching /swelling (especially of the face/tongue /throat), severe dizziness, trouble breathing .

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking vardenafil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as heart attack or life-threatening irregular heartbeat in the past 6 months, chest pain/angina, heart failure ), stroke in the past 6 months, kidney disease (dialysis), liver disease, high or low blood pressure. a severe loss of body water (dehydration), penis conditions (such as angulation, fibrosis/scarring, Peyronie’s disease ), history of painful/prolonged erection (priapism), conditions that may increase the risk of priapism (such as sickle cell anemia. leukemia, multiple myeloma ), eye problems (such as retinitis pigmentosa. sudden decreased vision, NAION), bleeding disorders, active stomach ulcers.

Vardenafil may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.

The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using vardenafil, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/”water pills”) or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using vardenafil safely.

This drug may make you dizzy or cause vision changes. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more sensitive to the side effects of this drug, especially QT prolongation (see above).

This medication is not usually used in women. Therefore, it is unlikely to be used during pregnancy or breast-feeding. Consult your doctor if you have any questions about this medication.

Interactions

See also How to Use section.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

A product that may interact with this drug is: riociguat.

Vardenafil can cause a serious drop in your blood pressure when used with nitrates, which can lead to dizziness, fainting, and rarely heart attack or stroke. Do not use vardenafil with any of the following: certain drugs used to treat chest pain/angina (nitrates such as nitroglycerin, isosorbide), recreational drugs called “poppers” containing amyl or butyl nitrite.

If you are also taking an alpha blocker medication (such as doxazosin, tamsulosin) to treat an enlarged prostate/BPH or high blood pressure, your blood pressure may get too low which can lead to dizziness or fainting. Your doctor may start treatment with a lower dose of vardenafil to minimize your risk of low blood pressure.

Other medications can affect the removal of vardenafil from your body, which may affect how vardenafil works. Examples include azole antifungals (such as itraconazole, ketoconazole), macrolide antibiotics (such as clarithromycin, erythromycin), HIV protease inhibitors (such as indinavir, ritonavir), hepatitis C virus protease inhibitors (such as boceprevir, telaprevir), rifampin, among others.

Many drugs besides vardenafil may affect the heart rhythm (QT prolongation), including amiodarone, procainamide, quinidine, sotalol, among others.

Do not take this medication with any other product that contains vardenafil or other similar medications used to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil).

Overdose

If overdose is suspected, contact a poison control center or emergency room right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: back/muscle pain, abnormal vision.

Notes

Do not share this medication with others.

Missed Dose

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Information last revised October 2015. Copyright(c) 2015 First Databank, Inc.

Images

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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Levitra (Vardenafil Hydrochloride)

What are Generics

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, how it is taken, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name and works the same way in the body in the same amount of time.

The only differences between generics and their brand-name counterparts is the generics are less expensive and may look slightly different (e.g. different shape or color), as trademark laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don’t have to invest large sums of money to invent a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name drug and sell it at substantial discounts.

Vardenafil Hydrochloride (Rx)
10mg Tablet

Manufactured by Sava Medica Ltd – Product of India – Shipped from Singapore – May be split

Vardenafil Hydrochloride (Rx)
20mg Tablet

Manufactured by Sava Medica Ltd – Product of India – Shipped from Singapore – May be split

(Rx) – indicates only available by prescription

To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3 month or 100 day supply based on your personal prescription. 1-888-791-3784 for assistance if your 100 day rule compliant desired quantity is not shown.”>read more

Vardenafil Hydrochloride Information

VARDENAFIL (var den a fil) is used to treat erection problems in men.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

Levitra® works to treat erectile dysfunction by improving blood flow to the penis. By taking Levitra®, you can get and keep an erection hard enough to have sex. The medicine works best if it is taken about one hour before sexual activity. Take the medicine only when you are about to have sex, and do not take more than one dose each day. This medicine is not supposed to be taken every day as a routine medicine. Do not take more than one dose each day and wait at least 24 hours between doses.

If you take the dose earlier, as much as two to three hours before sex, you should still be able to get and keep an erection. Levitra® only starts to work when you are sexually stimulated. Levitra® works best if you take it on an empty stomach about an hour before sex, but if you experience any stomach upset, it still works if you take it with food. The effect lasts for as long as six hours after taking the dose.

Erectile dysfunction can be caused by many things, but most people have physical problems that cause the condition. Examples of physical conditions include heart disease, high cholesterol, high blood pressure, and diabetes. Anxiety, stress, smoking, and alcohol use, can also contribute to problems with sexual performance.

Talk to your doctor about all your medical conditions and stressors to see if you have an underlying problem that can be treated to correct your erectile dysfunction.

Other prescription drugs that treat erectile dysfunction include:

Some men cannot take the drugs, or the drugs may not work for them. Other treatments are available for men that cannot take medicines for erectile dysfunction.

A medicine called alprostadil is available as a self-injection and is marketed under two brand names, Caverject® and Muse®. Alprostadil is also made in a suppository form that is inserted into the penis. Do not mix Levitra® with alprostadil.

Other options to treat erectile dysfunction include testosterone replacement medications and penis pumps. Surgical options include penile implants and blood vessel surgery.

Each prescription comes with a printed medication guide. Always take time to read the medication information in the guide provided by your online Canadian Pharmacy Referral Service to be sure you are reviewing the most recent information about your medicine.

A less expensive and safe generic alternative to Levitra, known as vardenafil, may be available. By using a Canadian Prescription Referral Service, we can help you find a licensed Canadian or international pharmacy that can provide you with safe generic products and the best possible dollar savings. As an added safety measure, we recommend purchasing your medicines from a pharmacy that is a member of the Canadian International Pharmacy Association. Visit a website called PharmacyChecker to locate licensed and credible pharmacies.

They need to know if you have any of these conditions: -bleeding disorders -eye or vision problems, including a rare inherited eye disease called retinitis pigmentosa -anatomical deformation of the penis, Peyronie’s disease, or history of priapism (painful and prolonged erection) -heart disease, angina, a history of heart attack, irregular heart beats, or other heart problems -high or low blood pressure -history of blood diseases, like sickle cell anemia or leukemia -history of stomach bleeding -kidney disease -liver disease -stroke -an unusual or allergic reaction to vardenafil, other medicines, foods, dyes, or preservatives -pregnant or trying to get pregnant -breast-feeding

Before buying Levitra® online, talk to your doctor about all your medical conditions, especially heart problems. Be sure your doctor agrees that it is safe for you to pursue sexual activity.

People that have liver and kidney problems may need to have their Levitra® dose adjusted. Talk to your doctor about your dose if you have liver and kidney conditions.

As with most medicines, interactions with other substances, including medicines prescribed by other doctors, over-the-counter products, vitamins, herbal supplements, and even alcohol use, can be dangerous. Give your doctor a complete list of everything you take.

Be sure you tell all your doctors or healthcare providers that you are taking Levitra®. All of your doctors need to know in order to prevent possible serious interactions with other medicines and medical conditions.

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You may take this medicine with or without meals. The dose is usually taken 1 hour before sexual activity. You should not take this dose more than once per day. Do not take your medicine more often than directed. Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others.

This does not apply.

Do not take this medicine with any of the following medications: -bepridil -certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole -cisapride -droperidol -grepafloxacin -medicines for irregular heartbeat like dronedarone, dofetilide -methscopolamine nitrate -nitrates like amyl nitrite, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin -nitroprusside -other medicines for erectile dysfunction like avanafil, sildenafil, tadalafil -pimozide -riociguat -thioridazine -ziprasidone This medicine may also interact with the following medications: -antiviral medicines for HIV or AIDS -certain antibiotics like erythromycin and clarithromycin -certain drugs for high blood pressure -medicines for prostate problems -other medicines that prolong the QT interval (cause an abnormal heart rhythm)

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

Examples of drugs that are nitrates include:

Common brand names for other medicines used to treat erectile dysfunction include:

Do not take Levitra® with medicines that have the same generic name but are used for other conditions. Examples include:

Poppers, known as street drugs, contain nitrates and should not be used with Levitra®

Some drugs can cause your heart rate to slow down too much when combined with Levitra®. Do not take Levitra® if you are taking any medicines that prolong a segment of your heartbeat called the QT interval. This interaction can be serious. Some examples of drugs that cause this to occur are listed here. This is not a complete list.

Examples of medicines that may become stronger when combined with Levitra® are listed here. This can mean that you may have side effects or an unwanted increase in the effect of the medication. A drop in your blood pressure is one of the unwanted effects of combining Levitra® with some of these agents

Some drugs can cause an increase in the effect of your Levitra® dose which can lead to unwanted side effects. Examples of medicines that can cause this type of interaction are listed below:

Some drug interactions can be life-threatening. Other interactions can cause unwanted side effects or make the medicines more or less effective. Sometimes drug interactions can cause a medicine to exceed safe levels in the blood, similar to taking an overdose. This can happen all at once or gradually over time. A drug interaction happens when one drug causes another drug to change how it works in the body.

Many processes are at work in your body that handle drugs. Interactions can happen at different places and for different reasons. Some processes involve how your gut absorbs the medicine, others involve the way your liver works to alter medicines. Some interactions occur at the exact place in your body where the drugs connect to do their job, and others involve changes with the way the drug is eliminated from your body.

Levitra® is no exception. There are many medicines that interact with Levitra®, or vardenafil, including alcoholic beverages and herbal products like St Johnís Wort.

Always ask your pharmacist to review your complete list of medicines, including over-the-counter drugs, vitamins, and herbal remedies, to be sure there are no drug interactions.

The pharmacists that fill your Levitra® prescription from a Canadian Prescription Referral Service also need a complete list of all your medicines. For your safety, they screen your current medicines with any new medicines you are getting filled online for possible dangerous drug interactions.

If you notice any changes in your vision while taking this drug, call your doctor or health care professional as soon as possible. Stop using this medicine and call your health care provider right away if you have a loss of sight in one or both eyes. Contact your doctor or health care professional right away if the erection lasts longer than 4 hours or if it becomes painful. This may be a sign of serious problem and must be treated right away to prevent permanent damage. If you experience symptoms of nausea, dizziness, chest pain or arm pain upon initiation of sexual activity after taking this medicine, you should refrain from further activity and call your doctor or health care professional as soon as possible. Do not drink alcohol to excess (examples, 5 glasses of wine or 5 shots of whiskey) when taking this medicine. When taken in excess, alcohol can increase your chances of getting a headache or getting dizzy, increasing your heart rate or lowering your blood pressure. Using this medicine does not protect you or your partner against HIV infection (the virus that causes AIDS) or other sexually transmitted diseases.

As with any new medicine, watch for signs of an allergic reaction. Symptoms can include swelling of the face, lips, tongue, or throat, difficulty breathing, tightening of the chest, and a skin rash, itching, and hives. Stop taking the medicine and call 911 or emergency medical help if you experience signs of an allergic reaction.

Side effects that you should report to your doctor or health care professional as soon as possible. -allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue -breathing problems -changes in hearing -changes in vision -chest pain -fast, irregular heartbeat -prolonged or painful erection -seizures Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome): -back pain -dizziness -flushing -headache -indigestion -muscle aches -nausea -stuffy or runny nose

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Stop sexual activity and call your doctor, 911, or emergency medical care, if you develop chest pain, dizziness, or nausea, during sex.

Some people have reported problems related to heart function. Let your doctor know immediately if you experience a change in your blood pressure or feel like your heart is beating too fast, too slow, or has an irregular rhythm. A quick drop in your blood pressure and changes in your pulse rate can be serious.

Keep out of the reach of children. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Vardenafil Hydrochloride Oral tablet

Erectile dysfunction is the inability to get or keep an erection. ED usually has a physical cause.

LEVITRA helps improve erectile function by increasing blood flow to the penis. LEVITRA has helped many men and it may help you, too.

LEVITRA can cause your blood pressure to drop suddenly to an unsafe level if it is taken with certain other medicines. With a sudden drop in blood pressure, you could get dizzy, faint, or have a heart attack or stroke.

If, like millions of other men, you have noticed changes in your erections, you can do something about it. Talking to your doctor is the first step.

Did you know
ED usually has
a physical cause?

Erectle Dysfunction Treatment – LEVITRA
See your doctor.

Indication
LEVITRA is a prescription medicine used for the treatment of erectile dysfunction (ED) in men.

Important Safety Information

  • LEVITRA can cause your blood pressure to drop suddenly to an unsafe level if it is taken with certain other medicines. With a sudden drop in blood pressure, you could get dizzy, faint, or have a heart attack or stroke.
  • Do not take LEVITRA if you:
    • Take any medications called “nitrates” (often used to control chest pain, also known as angina), or if you use recreational drugs called “poppers” like amyl nitrate and butyl nitrate. Nitrates may cause abnormally low blood pressure and LEVITRA may increase that risk
    • Take riociguat (Adempas ® ), a guanylate cyclase stimulator. a medicine that treats pulmonary arterial hypertension and chronic-thromboembolic pulmonary hypertension
    • Have been told by your healthcare provider not to have sexual activity because of health problems. Sexual activity can put an extra strain on your heart, especially if your heart is already weak from a heart attack or heart disease
  • Tell all your healthcare providers that you take LEVITRA. If you need emergency medical care for a heart problem, it will be important for your healthcare provider to know when you last took LEVITRA.
  • LEVITRA does not protect a man or his partner from sexually transmitted diseases, including HIV.
  • Before taking LEVITRA, tell your doctor about all your medical problems, including if you:
    • have heart problems such as angina, heart failure, irregular heartbeats, or have had a heart attack—ask your doctor if it is safe for you to have sexual activity
    • have low blood pressure or have high blood pressure that is not controlled
    • have pulmonary hypertension
    • have had a stroke
    • have had a seizure
    • or any family members have a rare heart condition known as prolongation of the QT interval (long QT syndrome)
    • have liver problems
    • have kidney problems and require dialysis
    • have retinitis pigmentosa, a rare genetic (runs in families) eye disease
    • have ever had severe vision loss, or if you have an eye condition called non-arteritic anterior ischemic optic neuropathy (NAION)
    • have stomach ulcers
    • have a bleeding problem
    • have a deformed penis shape or Peyronie’s disease
    • have had an erection that lasted more than 4 hours
    • have blood cell problems such as sickle cell anemia, multiple myeloma, or leukemia
    • have hearing problems
  • Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. LEVITRA and other medicines may affect each other. Especially tell your doctor if you take any of the following:
    • Ritonavir (Norvir ® ) or indinavir sulfate (Crixivan ® ), saquinavir (Fortavase ® or Invirase ® ) or atazanavir (Reyataz ® ), or other HIV protease inhibitors
    • Ketoconazole or itraconazole (such as Nizoral ® or Sporanox ® )
    • Erythromycin or clarithromycin
  • Tell your doctor if you take alpha-blockers. These include Hytrin ® (terazosin HCl), Flomax ® (tamsulosin HCl), Cardura ® (doxazosin mesylate), Minipress ® (prazosin HCl), Uroxatral ® (alfuzosin HCl), or Rapaflo ® (silodosin). Alpha-blockers are sometimes prescribed for prostate problems or high blood pressure. In some patients, the use of PDE5 inhibitor drugs, including LEVITRA, with alpha-blockers can lower blood pressure significantly, leading to fainting.
    • Contact the prescribing physician if alpha-blockers or other drugs that lower blood pressure are prescribed by another healthcare provider
  • Tell your doctor if you take medicines that treat abnormal heartbeat. These include quinidine, procainamide, amiodarone, and sotalol. Patients taking these drugs should not use LEVITRA.
  • Do not use LEVITRA with other medicines or treatments for ED.
  • Take LEVITRA exactly as your doctor prescribes. LEVITRA comes in different doses (2.5 mg, 5 mg, 10 mg, and 20 mg). For most men, the recommended starting dose is 10 mg. Do not take more than one tablet of LEVITRA per day. Doses should be taken at least 24 hours apart. Some men can take only a low dose of LEVITRA because of medical conditions or medicines they take. Your doctor will prescribe the dose that is right for you.
    • If you are older than 65 or have liver problems, your doctor may start you on a lower dose of LEVITRA
    • If you have prostate problems or high blood pressure for which you take medicines called alpha-blockers, your doctor may start you on a lower dose of LEVITRA
    • If you are taking certain other medicines, your doctor may prescribe a lower starting dose and limit you to one dose of LEVITRA in a 72-hour (3-day) period.
  • The most common side effects with LEVITRA are headache, flushing, stuffy or runny nose, indigestion, upset stomach, dizziness, and back pain.
  • LEVITRA may uncommonly cause:
    • An erection that lasts more than 4 hours. Get medical help right away to avoid lasting damage to your penis
    • Color vision changes. such as seeing a blue tinge to objects or having difficulty telling the difference between the colors blue and green
  • In rare instances, men taking PDE5 inhibitors (oral erectile dysfunction medicines, including LEVITRA) reported a sudden decrease or loss of vision in one or both eyes or a sudden decrease or loss in hearing, sometimes with ringing in the ears and dizziness. It is not possible to determine whether these events are related directly to the PDE5 inhibitors, to other diseases or medications, to other factors, or to a combination of factors. If you experience sudden decrease or loss of vision or hearing, stop taking LEVITRA and contact a doctor right away.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please read the Patient Information and discuss it with your doctor.

The physician Prescribing Information is also available.

NOTE: All trademarks are the property of their respective owners.

�Adobe is a registered trademark of Adobe Systems incorporated.

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